Breath test analysis

Breath test methods are roughly divided into direct measurement of breath components and indicative breath test.Testing), direct testing of respiratory components includes single indicator measurement and analysis and respiratory fingerprinting. Breath test is a common test method used to detect lung function and disease by analyzing the air exhaled by the human body. In addition to main components such as carbon dioxide, the air exhaled by the human body also contains various impurities. The type and content of these impurities can reflect the physiological health of the human body. Respiratory diagnostic technology is a multidisciplinary emerging technology that diagnoses diseases by measuring the impurity content in human breath. It has outstanding advantages such as non-invasive, accurate, hygienic and convenient.

The principles of breath testing are based on the following aspects:

(1)Air composition analysis: Exhaled air contains oxygen, carbon dioxide, nitrogen and other components, of which the carbon dioxide concentration is stable and measurable. By measuring changes in carbon dioxide concentration in exhaled air, a patient's lung function can be determined.

(2)Lung volume measurement. Lung volume can be measured by the total amount of air exhaled and the time it takes to breathe out. Exhalation flow meters and other devices can measure the flow and time of exhaled air to obtain exhaled volume.

(3)Gas diffusivity. By measuring carbon monoxide and oxygen in the air, the gas diffusivity in the lungs can be determined. By measuring changes in carbon monoxide and oxygen levels after expiration, you can determine the ability of the lungs to diffuse gas.

(4)Lung function damage testing. Breath tests can be used to detect various lung function impairments, such as asthma, emphysema, pneumonia, etc. These lung diseases affect air flow and lung volume, which in turn affects the gas composition in the exhaled air.

A test method that determines lung function and disease by analyzing changes in composition and volume in exhaled air. Through scientific principles and appropriate equipment, breath testing can provide patients with accurate and effective lung test results, helping doctors correctly diagnose and treat lung diseases.

For example, the C13 Helicobacter pylori breath detector can clearly detect whether a patient is carrying Helicobacter pylori and the number of bacteria by just breathing in. An infrared breath detector based on DFB laser technology can accurately measure the trace concentration of specific gas components in human breath, thereby quickly detecting the occurrence of a certain disease. This paper reports the application of continuous near-infrared or mid-infrared laser and quartz-enhanced photoacoustic spectroscopy in clinical respiratory analysis. The detection sensitivity is 20 ppb and the temporal resolution is 0.3 S.